Commonly known as “runner’s knee,” piriformis syndrome happens when the sciatic nerve is compressed or irritated, causing pain in the butt, thigh, and lower leg. This pain is often worse when sitting and can make it difficult to sit for any length of time, let alone exercise.
Whether you have a desk job or you’re a professional runner, you have to be active to live a healthy life. But, if you’re suffering from sciatica, it can be hard to continue exercising.
Read on for our list of the best mattress for piriformis syndrome, so you can sleep comfortably no matter what activity you’re doing.
Our Editor’s Best Mattress For Piriformis Syndrome Reviews
LOUTYTUO Seat Cushion Pillow,100% Memory Foam and Washable Cover,for Office Chair,Car Seat and Wheelchair,Tailbone & Sciatica & Back Pain Relief

Key Features:
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This mattress is made of 100% memory foam, which is designed to be soft and comfortable while providing support. It is perfect for people who spend a lot of time driving or sitting.
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This mattress is designed to help with piriformis syndrome by providing support for the lower back and neck, and by alleviating pressure on the tailbone.
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The mattress is designed to provide relief for piriformis syndrome and comes with a detachable, washable cover. The cover is colorfast and won’t bleed in the wash, so you can machine-wash it with other clothes without worrying about staining your pants and chair.
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The 3D Spacer Mesh mattress is designed to help with ventilation and keep the cushion from getting too warm to discharge excess heat from your body. It also won’t retain odors and smells.
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If you are looking for a mattress that will help alleviate pain from piriformis syndrome, this is a great option. It is designed to fit all types of chairs, and is perfect for people who spend a lot of time sitting, such as office workers and drivers.
Cushy Tushy Premium Foldable Piriformis Cushion – Piriformis Pain and Sciatic Pain Relief Cushion – for Home & Office Use, Perfect for Travel or Driving – Piriformis Cushion

Key Features:
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This mattress is specifically designed to provide relief from piriformis syndrome and sciatic pain. It features a one-of-a-kind patented design that isolates and removes pressure from the piriformis muscle and outer hip area, allowing the muscle to relax and relieving sciatic pain, pressure, and inflammation.
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This mattress is designed to provide relief from piriformis syndrome, a condition that can cause pain in the buttocks. The mattress is foldable and comes with a travel bag, making it easy to take with you on the go. The mattress is also discreet, so you can use it without drawing attention to your condition.
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This mattress is designed to provide comfort and support for people with piriformis syndrome. It is made of memory foam that is dense and firm, and is ergonomically designed to provide the perfect balance of support and comfort.
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If you are looking for a mattress to help with piriformis syndrome, lower back pain, herniated discs, tailbone injuries, sciatica, or other spine related issues, this contoured support mattress may be a good option for you. It is designed to evenly distribute your body weight and help you maintain good posture, relieve spinal pressure, and minimize pain, muscle fatigue, and leg tightness.
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This mattress is a pillow designed to relieve pain in the lower back and buttocks by cushioning the pressure points. It is made of memory foam and is covered in a soft, breathable fabric. It is easy to travel with and comes with a satisfaction guarantee.
Zinus 12 Inch Green Tea Memory Foam Mattress / CertiPUR-US Certified / Bed-in-a-Box / Pressure Relieving, Queen

Key Features:
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This mattress is made specifically for people with piriformis syndrome. It is memory foam, so it will expand in a warmer room and take a bit longer to return to full size in cold temperatures.
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If you’re looking for a mattress to help with piriformis syndrome, this one from Zoma might be a good option. It’s made with pressure-relieving memory foam and infused with refreshing green tea and ActivCharcoal, which are both said to help with absorbing moisture.
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This mattress is designed to provide pressure relief for people with piriformis syndrome. It features three layers of foam, including a memory foam layer that conforms to the body, a soft comfort layer that enhances airflow, and a durable base support layer.
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This mattress is made with high-quality foam that is CertiPUR US Certified for durability, performance, and content. This mattress is ideal for people with piriformis syndrome because it offers support and comfort while alleviating pressure on the hips and buttocks.
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This mattress is designed to provide relief for piriformis syndrome sufferers. It is made of memory foam and is shipped in a compressed state. Once it is unrolled, it will expand to its full size and shape within 72 hours.
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This mattress is designed to provide support and relief for people suffering from piriformis syndrome. It includes a 10 year limited warranty, and can support up to 500 lbs.
ProsourceFit Ki Acupressure Mat and Pillow Set with 100% Natural Linen for Back/Neck Pain Relief and Muscle Relaxation

Key Features:
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If you suffer from piriformis syndrome, this mattress is designed to help reduce muscle tension and back pain. Simply lay on the mat for 10-30 minutes each day to see results.
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This mattress is designed to provide full support for your back and neck, with a cushioned foam mat and an acupressure pillow. It is large enough to fit your full back, and it is designed to provide holistic pain relief.
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This mattress is specifically designed to relieve stress and tension in the muscles by massaging pressure points. It can be used before bedtime to improve sleep quality.
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This mattress is designed to relieve pain in the lower back and buttocks by stimulating nerves and improving circulation. It is especially beneficial for people who sit for long periods of time or are active athletes.
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This mattress is made out of 100% high quality thick cotton and plant-based interior: foam. The acupressure mat has 6,210 acupressure points; neck pillow has 1,782 acupressure points. Material: ABS plastic. You will quickly become accustomed to the sensation of the spikes.
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This mattress is designed to provide relief for piriformis syndrome. It is made of memory foam and has a medium-firmness. The cover is removable and machine-washable. The mattress is available in twin, full, queen, and king sizes.
TushGuard Seat Cushion for Office Chair Memory Foam Non-Slip Desk Chair Cushion Back, Coccyx, Sciatica, Tailbone Pain Relief Butt Pillow for Office Chair, Car, Wheelchair, Black

Key Features:
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If you’re looking for a mattress that will help with piriformis syndrome, this one is a great option. It’s made of memory foam, which adapts to your curves and provides superior comfort. It also helps with muscle fatigue. The memory foam never loses its shape, and it slowly rebounds to its original shape after use.
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The mattress is designed to provide relief for piriformis syndrome by alleviating pressure on the sciatic nerve. The mattress has a rubber bottom to prevent slipping, a built-in handle for easy portability, and a removable cover for easy cleaning. The mattress also has a breathable mesh cover to allow air to circulate and prevent heat from collecting.
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This mattress is designed to help with piriformis syndrome by increasing blood flow and supporting good posture. It is popular with people who sit for more than 8 hours a day.
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The mattress is designed to provide extra support to your body and relieve pressure on your spine, back, and sciatic nerve. It is effective at relieving back, coccyx, sciatica, and tailbone pain.
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This ergonomic seat cushion is designed to provide comfort for people who sit in chairs and face screens all day. It is great for office work, gaming, watching movies, and more. If you travel by car, train, or plane and find the seats uncomfortable, this portable cushion will be your best travel partner. It will bring extra comfort to your office, car, or chair!
Aylio Socket Seat – Memory Foam Comfort Cushion for Butt and Tailbone Relief, Posture, Hip, Hamstring, Lower Back Pain Pillow – Sit Bone Ischial Tuberosity Seat Cushion

Key Features:
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The Socket Seat is an ergonomic mattress designed to take pressure off of the tailbone, piriformis, and sitz bones. It is made of high-density foam and is covered in a soft, breathable fabric. The mattress is available in a variety of sizes to fit any bed.
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The mattress is designed to provide relief for pain in the buttocks, ischial bursitis, hip bursitis, and hamstring tears.
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The mattress for piriformis syndrome is a high-density memory foam mattress that is designed to provide the best possible support and comfort for people suffering from the condition. The mattress is made from a variety of high-quality materials, including high-density memory foam, 3D airflow mesh, and durable vegan leather. The mattress also features soft velvet accents that add to its overall comfort and support.
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This mattress is designed to provide comfort and support for people with piriformis syndrome. It is a one-size-fits-all mattress that is 14.5 x 18.5 x 3 inches in size.
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This mattress is specifically designed to provide relief for piriformis syndrome sufferers. It features a 100 day risk-free trial from the manufacturer, so you can try it out and see if it helps ease your pain.
Everlasting Comfort Seat Cushion – Office Chair Cushions w/ 30% More Memory Foam for All-Day Sitting Comfort – Ergonomic Coccyx, Back, Tailbone Pain Relief Pad Pillow Support for Car Seat, Desk Chair

Key Features:
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This mattress is designed to provide relief from piriformis syndrome by using pure memory foam to adapt to the curves of your body. It is also designed to give you the support your current office chair lacks.
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This mattress is designed to prevent bottom sweats by allowing air to circulate and keeping the user cool.
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This chair cushion is designed to stay in place, even if you shift around in your seat. It has a non-slip rubber bottom, so it won’t slide out from under you. This can be helpful for piriformis syndrome, as it can provide support and stability for your hips and pelvis.
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This mattress is designed to stay fresh and clean, making it ideal for people with piriformis syndrome. The removable cover is machine washable, making it easy to keep the mattress clean.
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If you are looking for a mattress to help with piriformis syndrome, this mattress is a good option. It is made of memory foam, which will mold to your body and provide support where you need it. Additionally, the foam is slow rebounding, so it will always go back to its original shape.
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If you suffer from piriformis syndrome, this mattress is designed to provide you with comfort and relief from pain. It features a cushioned seat that cradles your bottom and reduces pressure points in your lower body, providing support for your lower back, hips, and sciatic nerve.
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This mattress is designed to relieve pressure on the tailbone and improve posture. It is made with an ergonomic “U” shaped cutout that suspends the coccyx above hard seating surfaces.
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This mattress is made with certified safe materials and is designed to help relieve pain associated with piriformis syndrome.
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The mattress is designed to relieve pressure on the piriformis muscle, which can become irritated and cause pain in the buttocks. The mattress is large enough to fit all types of chairs, and has a firmness that can be adjusted to provide the best support for the user.
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This mattress is designed to relieve pain in the piriformis muscle, which can cause sciatica. It can be used as a seat cushion, desk chair cushion, or pillow for back pain. It is also great for travel, as it can be used to sit comfortably wherever you go.
PSO-RITE Psoas Muscle Release and Deep Tissue Massage Tool – Psoas, Back, Hip Flexor Release Tool – Night Black

Key Features:
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The PSO-Rite is a self-care tool that can help with piriformis syndrome by massaging and releasing the psoas complex. This can help with regulating the fight or flight response, supporting digestive organs, regulating breathing, and aiding in pumping blood and lymph through the body.
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The PSO-Rite mattress is designed to provide relief for piriformis syndrome by mimicking the pressure and hardness of a massage therapist’s elbow. It is a handheld tool that can be used any time to release muscle tension in the hip region.
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The PSO-Rite deep tissue massage tool is specifically designed to use one peak at a time on each psoas muscle, making it just as effective at releasing tightness in nearly every muscle of the body. It can be used on the hamstrings, thigh, inner thigh, calf, glutes, lower back, upper back, triceps, biceps, and chest. The shopper is the one in control of the pressure.
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The PSO-Rite is a deep-tissue massage tool that can be used anywhere, anytime. It is perfect for piriformis syndrome sufferers as it helps to relieve pain and tension in the muscles.
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This mattress is designed to provide relief for piriformis syndrome by allowing the user to adjust the amount of time spent in any given position. The dimensions of the mattress are 10.7″ long, 5″ wide, and 5.3″ tall, with a peak to peak of 6.3″. It weighs 1.15 lb.
Coccyx Cushion Pillow For Chairs | Pain Relief From Back Sciatica Pinched Nerve Piriformis Syndrome Lumbosacral Spondylosis Fibromyalgia and Bruised Tailbone | Medical Grade by Med-X

Key Features:
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The mattress is designed to provide support for the lower back and tailbone, alleviating pressure and pain. It is shaped like a U with a cut-out in the center, and can be used in a variety of settings such as office chairs, wheelchairs, recliners, and cars.
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This mattress is for people who suffer from piriformis syndrome, a condition that causes pain in the buttocks. The mattress is made of memory foam and is contoured to reduce pressure on the coccyx or tailbone.
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This mattress is designed to alleviate pain in the lower back and tailbone area by promoting healthy posture and weight distribution. It is made of a firm, supportive material that will provide comfort and relief for those suffering from piriformis syndrome.
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This is a coccyx seat cushion that is portable and easy to travel with. It is covered with a black, removable velveteen fabric cover that is washable. The non-skid bottom helps keep it in place on all types of office chairs, wheelchairs, car and airplane seats.
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The mattress is designed to provide relief for piriformis syndrome sufferers by alleviating pressure on the sciatic nerve. The 100% lifetime refund policy ensures that shoppers are satisfied with their purchase.
Cushy Form Knee Pillow for Side Sleepers – Standard Orthopedic Wedge Leg Pillow for Sleeping and Hip & Lower Back Pain – Contour Memory Foam Cushion for Pregnancy, Washable Cover & Travel Bag, White

Key Features:
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If you suffer from piriformis syndrome, this mattress is perfect for you! The contour knee wedge is made with premium memory foam to elevate your upper knee and help you sleep comfortably through the night. Additionally, the therapeutic leg pillows encourage better posture, making this mattress perfect for those who suffer from this condition.
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This mattress is designed to reduce pressure on the joints and ease back, leg, knee, ankle, and hip pain. It is also effective for relieving discomfort associated with sciatic nerve pain.
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This mattress is specifically designed to provide relief for piriformis syndrome. It is made of comfortable materials and includes a washable cover and storage bag for travel.
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This mattress is designed to provide support for people with piriformis syndrome. It is extra-wide to provide support for both legs and each foot.
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This mattress is specifically designed to provide relief for piriformis syndrome, a condition that causes pain in the hip and buttocks. The mattress is made of high-quality memory foam that will contour to your body and provide support where you need it most.
Mattress For Piriformis Syndrome FAQs
1. What is the best mattress for piriformis syndrome?
There is no definitive answer to this question as each person’s experience with piriformis syndrome may be different. Some people may find that a firmer mattress provides the most support and comfort, while others may prefer a softer mattress. Ultimately, it is important to find a mattress that is comfortable and provides the necessary support to help alleviate pain associated with piriformis syndrome.
2. What are the symptoms of piriformis syndrome?
The main symptom of piriformis syndrome is pain in the buttock. The pain is often described as deep and aching. It may be worse when sitting or lying down. Other symptoms can include pain in the hip, thigh, or groin. The pain may get worse when walking or moving the affected leg.
3. What causes piriformis syndrome?
There is no one definitive answer to this question as the condition can be caused by a variety of things, ranging from overuse or injury to the muscle itself, to problems with the alignment of the hip or pelvis. In some cases, it may also be caused by a herniated disc or other issue in the lower back.
4. How is piriformis syndrome diagnosed?
Piriformis syndrome is difficult to diagnose because the symptoms are similar to other conditions, such as sciatica. A doctor may order imaging tests, such as an MRI, to rule out other conditions. The doctor may also ask the patient to perform certain movements to see if they cause pain.
5. How is piriformis syndrome treated?
There is no one-size-fits-all answer to this question, as the treatment for piriformis syndrome will vary depending on the underlying cause of the condition. However, some common treatments for piriformis syndrome include physical therapy, stretching exercises, massage, and ice or heat therapy. In severe cases, surgery may be necessary to release the piriformis muscle from the sciatic nerve.
Conclusion
There are many great mattress for piriformis syndrome on the market. Our list of the best mattress for piriformis syndrome will help you save time researching and choosing the best one for you.